Supreme Rejuvenation


At Supreme Rejuvenation, we stand at the forefront of the science and technology industry, pioneering groundbreaking innovations to redefine healthcare. Our product range is meticulously crafted not only to enhance physical and mental performance but also to elevate energy levels and overall vitality, delivering tangible benefits for both patients and practitioners.

Our Vision: Cultivating Bio-Wellness for Holistic Well-Being

Our overarching goal is to foster a culture of bio-wellness, seeking harmony within the mind, body, and cellular processes. Through comprehensive education, we aim to kindle a passion for optimizing bodily functions, improving health, and unlocking an individual’s fullest potential.

The Heart of Our Offerings: MSC Exosome Product Line

Central to our offerings is the MSC exosome product line. These exceptional exosomes are intricately designed to elevate the body’s performance, enabling individuals to achieve health and life goals with unprecedented efficacy.

Firm Beliefs: Balance and Vitality for a Fulfilling Life

At Supreme Rejuvenation, we firmly believe that balance and vitality are the cornerstones of a fulfilling life. We are wholly dedicated to providing the necessary tools and knowledge for individuals to embark on transformative journeys toward better health and well-being.

About Us

Our Commitment to Excellence: Ensuring Regulatory Compliance and Quality Assurance

  • We exclusively offer regenerative medicine products meeting stringent FDA 351(a) drug regulations, ensuring the highest level of regulatory compliance.
  • Pioneering regulatory compliance as a Biologic Drug for Research and Investigational Purposes.
  • Rigorous third-party testing accompanies every product shipment, including Endotoxin and Mycoplasma Reports, Sterility Reports, Nanoparticle Tracking Analysis (N.T.A.), and Proteomics Assays to assess relevant proteins.
  • Our regenerative medicine product, meticulously designed to target inflammation and repair damaged tissues, caters to diverse needs from hair growth and wound care to addressing Traumatic Brain Injury, joint and ligament repair, Botox alternatives, IV infusions, and treatment for approximately 150 different ailments.
  • Rest assured, every batch is NTA and CD81 Protein Tested, guaranteeing a quantity of 28 billion units per millimeter/cubic centimeter (mL/cc).

Join us in the journey towards a healthier and more vibrant future.

Supreme Rejuvenation

24 Hr Delivery

3rd Party Virology Test


Experience the extraordinary power of our patented Exosome technology in Supreme Rejuvenation’s Topical Gel. Our unique patented technology not only harnesses the potential of Exosomes but also extends the shelf life of the topical gel to an impressive 18 months at room temperature, offering unmatched convenience.

Exosomes, small vesicles secreted by stem cells, are the driving force behind this innovation. Packed within these tiny vesicles are substantial quantities of growth factors, cytokines, and other bioactive substances with remarkable regenerative potential. What sets them apart is their exceptional structure, which enables the transfer of these rejuvenating elements to other cells.

This groundbreaking technology opens doors to a new era in skincare and regenerative therapy. It’s not just a topical gel; it’s a testament to scientific advancement that empowers your skin and enhances your well-being.

Human Umbilical Cord Stem Cell Derived Exosome

Sterile Saline 100 Billion Exosomes per 5cc

At Supreme Rejuvenation, our sterile saline serum harnesses the remarkable potential of exosomes, tiny vesicles secreted by stem cells. These exosomes possess a unique structure that enables them to fuse with other cells within the body, facilitating the release of their potent contents. These contents include cytokines, growth factors, and mRNA, which act as signaling molecules, triggering a cascade of regenerative processes within the target cells. This intricate mechanism essentially empowers the cells to heal themselves.

What sets exosomes apart from stem cells is their distinctive characteristics. Exosomes do not replicate, contain DNA, or induce an immune response. Consequently, our serum is a safer alternative when compared to stem cell therapies. Importantly, exosome products are inherently cell-free and contain no live cells by definition, ensuring safety and efficacy.

Moreover, our injectable product offers unparalleled convenience. It can be stored in a regular freezer (-20°C) for up to 3 months before requiring cryo-freezer (-80°C) storage, extending its shelf life to an impressive 18 months. Remarkably, it can also be refrozen up to three times without compromising its potency.

At Supreme Rejuvenation, we pride ourselves on offering the safest and most potent exosome products on the market, driven by cutting-edge science and innovation.


At Supreme Rejuvenation, we take pride in offering cutting-edge therapeutic solutions for scarless wound restoration. Our MSC exosomes play a pivotal role in this process by controlling the ratios of collagen and fibroblast differentiation. This control significantly reduces the likelihood of scarring, making our exosomes a revolutionary approach to wound healing.

MSC exosomes support the rebuilding of cutaneous wounds in a way that promotes scarless outcomes. These tiny vesicles facilitate tissue growth, regenerate injured tissues, and actively engage in the process of tissue regeneration. This unique mechanism accelerates the healing process, delivering results that go beyond conventional treatments.

Importantly, MSC exosomes offer several advantages. They act as powerful mediators, orchestrating cellular processes without the need for stem cells. This makes our exosome therapy safe and highly effective. Furthermore, MSC exosomes don’t contain DNA, minimizing the risk of adverse immune responses.

Our commitment to advancing regenerative medicine is exemplified by the innovative use of MSC exosomes in scarless wound restoration. Supreme Rejuvenation’s MSC exosomes represent a groundbreaking approach to wound healing and tissue regeneration, setting new standards in the field.

Facial Firming Serum with Exosomes

100 Billion Exosomes/15ml
200 Billion Exosomes /30ml

Aloe Leaf Juice, Alcohol, DMAE bitartrate, Jojoba Seed Oil, Emulsifying Wax, Glycerin, MSM, Rooibos Leaf Extract, Hyaluronic Acid, Green Tea Leaf Extract, White Tea Leaf Extract, White Willow Bark Extract, Vitamin E, Sunflower Seed Oil, Vitamin B3, Xanthan Gum, Human Umbilical
Cord Mesenchymal Stem Cell Derived Exosomes, Cytokines and Growth Factors.

Vitamin Serum with Exosomes

100 Billion Exosomes/15ml
200 Billion Exosomes /30ml

Organic Aloe Leaf Juice (Aloe barbadensis), Glycerin, Vitamin B3 (Niacinamide), Emulsifying Wax (Cetyl Alcohol, Stearyl Alcohol, Polysorbate 60), Avocado Fruit Oil (Persea gratissima), Hyaluronic Acid, Vitamin E (Tocopherol), Sunflower Seed Oil (Helianthus Annuus), Organic Neem Seed Oil (Melia azadirachta), Organic Rosemary Leaf Extract (Rosmarinus officinalis), Organic Sunflower Seed Oil (Helianthus annuus), Xanthan Gum, Phenoxyethanol, Tetrasodium Glutamate Diacetate, Human Umbilical Cord Mesenchymal Stem Cell Derived Exosomes, Cytokines and Growth Factors.

What Are Exosomes

Exosomes, these remarkable entities, are intricately involved in cellular communication and regenerative processes. They are minute vesicles originating from various cell types, including stem cells. These tiny packages are bestowed with an extraordinary capacity to contain and transport a diverse range of bioactive molecules.

Within the confines of exosomes lie substantial quantities of growth factors, cytokines, and an array of other bioactive substances. It’s this rich molecular payload that imparts upon exosomes their unique regenerative potential. What truly sets exosomes apart is their exceptional structure that enables them to transfer these bioactive cargo to neighboring cells.

This transfer of regenerative signals is pivotal in the world of cellular health. Exosomes act as nature’s messengers, facilitating intercellular communication. When they fuse with target cells, they deliver their payload, thereby kickstarting processes that promote tissue repair, regeneration, and growth.

How They Work

Stem cell-derived exosomes are the unsung heroes of regenerative medicine, orchestrating the body’s healing processes in a fascinating way. Here’s a closer look at how they work:

  1. Identification of Injury: When tissue is injured, it releases chemical markers indicating the extent of damage. These markers act as distress signals.

  2. Stem Cell Response: Stem cells, with their remarkable sensing abilities, pick up on these signals. They “know” that specific repair components are needed.

  3. Customized Healing Components: Stem cells swing into action, producing the precise components required for healing the injured tissue. This includes growth factors, cytokines, and more.

  4. Packaging in Exosomes: These components are meticulously packaged into tiny vesicles known as exosomes. Think of exosomes as tiny delivery vehicles loaded with healing cargo.

  5. Guided Delivery: Exosomes are released by stem cells and migrate to the site of the injured tissue. They’re like GPS-guided messengers, pinpointing the area that needs repair.

  6. Healing Handover: Once at the injury site, exosomes attach themselves. Then comes the magic moment when they release their healing contents directly to the injured tissue.

The result? Remarkable tissue healing and regeneration. Stem cell-derived exosomes have shown incredible efficacy in various studies, from peripheral nerve damage and traumatic brain injury to wound healing, bone fusion, and more. They possess anti-inflammatory properties and play vital roles in skin, cartilage, and bone regeneration, making them versatile assets in regenerative medicine.

Despite their proven effects, it’s worth noting that, as of now, there are no FDA-approved exosome products available in the United States. Researchers continue to explore their potential and safety in clinical applications.

This is how stem cell-derived exosomes work their magic, offering promising avenues for cutting-edge therapies and tissue repair.

Why Use Umbilical Cord Msc Derived Exosomes

Understanding the complexities and limitations of using live stem cells in medical treatments is crucial. Here’s an improved explanation:

Regulatory Complexity: Live stem cells carry significant medical risks, leading to stringent regulation. Presently, their lawful use is restricted to two scenarios: when derived from the patient’s own body or when they remain unaltered for tissue transplantation. However, these methods have inherent drawbacks beyond health risks.

  1. Tissue Specificity: Tissues used for transplantation can only be applied to similar tissues. For instance, placental membranes are limited to skin-type tissues, restricting their versatility.

  2. Aging and Diminished Efficacy: Self-derived stem cells are prone to age-related degradation. Typically, by the age of 40, the efficacy of a person’s stem cells starts declining. This decline is even more pronounced in patients around 60, precisely the age when many require stem cell therapies.

To overcome these limitations, we employ a cutting-edge approach:

Umbilical Cord Mesenchymal Stem Cells: We utilize umbilical cords from newborns to extract mesenchymal stem cells. These stem cells are exceptionally unique and potent.

Laboratory Control: These extracted cells undergo rigorous screening and culture in our state-of-the-art laboratory. This process ensures the safety and effectiveness of the cells.

Exosome Secretion: We immerse these stem cells in a carefully designed medium that prompts them to secrete exosomes. These exosomes contain consistent and abundant regenerative factors.

Quality Assurance: The exosomes are then extracted and subjected to batch testing. This meticulous analysis ensures their safety and effectiveness.

These exosomes, brimming with regenerative potential, become valuable tools for further research and innovative medical treatments. This approach addresses the limitations of live stem cell usage and offers promising avenues for advanced therapies.

Research results

“At Supreme Rejuvenation, we take immense pride in being the exclusive representative of the only human umbilical cord-derived exosome company registered as a biological drug in the United States. What sets us apart is our unwavering commitment to the highest standards of safety and efficacy, coupled with rigorous testing and stringent FDA regulatory oversight.

Our dedication to excellence means that we offer the safest and most potent human umbilical cord-derived exosomes available on the market. Our exosomes are officially registered as a 351(a) biologic product, enabling us to offer them for research and investigational use. We go above and beyond in ensuring the quality of our product, subjecting it to comprehensive testing, and obtaining third-party virology reports to guarantee its safety and efficacy.

Our exosomes have garnered recognition for their positive impact across a wide spectrum of medical fields, including cardiology, aesthetics, plastic surgery, multiple sclerosis, cerebral palsy, and more. Studies affirm their effectiveness in treating cardiovascular disease by promoting angiogenesis and reducing inflammation. Additionally, our exosomes excel in promoting healing and reducing scarring in plastic surgery procedures. They have also exhibited remarkable potential in improving the symptoms of patients with conditions like multiple sclerosis, cerebral palsy, and stroke.

Beyond these areas, our exosomes have proven instrumental in enhancing sexual function in both men and women. Dr. Goldstein’s study underscores their role in improving erectile function and sexual desire in men with erectile dysfunction. Furthermore, our exosomes have demonstrated the ability to enhance vaginal lubrication and overall sexual function in women.

Choose Supreme Rejuvenation for a transformative experience that brings the highest quality and innovation to regenerative medicine.”

In the field of aesthetics, our exosomes have been shown to improve skin texture, reduce wrinkles, and stimulate hair growth. In a study conducted by Dr. Berman, our exosomes were found to stimulate hair growth in patients with androgenetic alopecia.

Furthermore, our exosomes have been shown to have neuroprotective effects and can promote nerve regeneration in conditions such as optic nerve damage and glaucoma. Studies have also shown that our exosomes can improve symptoms in patients with COVID-19 long-haulers and dementia.

In orthopedics, our exosomes have been shown to reduce inflammation and promote cartilage regeneration, making them effective in treating arthritis and other joint-related conditions. Our exosomes have also been shown to improve outcomes in spinal cord injuries.

We take pride in the quality of our product and the studies that support its efficacy. Our exosomes are the result of years of research and development, and we are committed to providing thehighest quality product to our customers. To learn more about the studies mentioned above, please see the links below:

Future Products

We are pursuing the following future product lines and are looking forward to getting appropriate FDA clearances to allow sales and distribution of these products soon.


For FDA Devices/saline.


Dropper bottle with calibrated dropper


Case of 20x 5ml eye droppers


Dropper bottle for use with a nebulizer


Packaging to be determined


Pressurized Inhaler


Hydro Gel in a medical spray, possibly coupled with a bandage S


Spray Bottle For Nasal Inhalation


Spray Specialized applicator


Utilizing Hydro Gel

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